Differential effect of panic on the DNA methylation of the glucocorticoid receptor gene exon 1F in chronic subjective tinnitus with distress.

Psychiatr Genet · 2023 · PMC10325559 · PMID 37222222

Europe PMC DOI

hedged sentences

0.0180

closest p · 0.4× alpha

0.0800

boldest claim

The sentences

approached significanceP = 0.018actually significant

Because the difference in BMI among the subgroups approached significance (Supplementary Table 3, Supplemental digital content 3, http://links.lww.com/PG/A299 P = 0.018), we added BMI as a covariate to the linear mixed model to account for this parameter in the association between methylation and tinnitus status.

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a trend towards significanceP = 0.08so close (0.05 < p ≤ 0.1)

The difference with the control group was significant ( P = 0.030 following Tukey correction for multiple testing), whereas the difference with the tinnitus-only group, though in the same order of magnitude, only showed a trend towards significance ( P = 0.08).

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showed a trendP = 0.08so close (0.05 < p ≤ 0.1)

The difference with the control group was significant ( P = 0.030 following Tukey correction for multiple testing), whereas the difference with the tinnitus-only group, though in the same order of magnitude, only showed a trend towards significance ( P = 0.08).

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