Support vector machine learning and diffusion-derived structural networks predict amyloid quantity and cognition in adults with Down's syndrome.

Longitudinal change in total recall performance was nominally significant ( p = 0.04) between the PiB + and PiB − groups, and total recall at baseline was also significantly different between groups ( p < 0.01) indicating, as expected, a more overt cognitive decline was present in the individuals with positive PiB scans.

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