highly significantp ≤ 0.0001
In the early group linsitinib had a highly significant effect on GD development (p ≤ 0.0001) ( Figure 9E ).
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Linsitinib, an IGF-1R inhibitor, attenuates disease development and progression in a model of thyroid eye disease.
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0.0001
0.1900
The sentences
showed a trendp= 0.19
Linsitinib significantly reduced T-cell infiltration in the orbital fat of the late TSHR-immunized mice ( Figure 5B ), while the early group showed a trend to reduced T-cell infiltration after treatment with linsitinib (p= 0.19).