Barely Significant
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Genome-wide association analysis and Mendelian randomization proteomics identify drug targets for heart failure.

Nat Commun · 2023 · PMC10333277 · PMID 37429843

Europe PMCDOI
1
hedged sentence
0.0500
closest p · 1.0× alpha
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boldest claim

The sentences

nominally significantp value <0.05actually significant
In a replication study of the 18 novel loci, findings from the HF GWAS in the GBMI multi-ancestry excluding UK Biobank indicate 33.3% (6 of 18) of variants are significant ( p value <0.05/18), 61.1% (11 of 18) are nominally significant ( p value <0.05), and 100% have a beta estimate that is directionally concordant with our meta-analysis (Supplementary Data 20 ).

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