Targeting the glycine-rich domain of TDP-43 with antibodies prevents its aggregation in vitro and reduces neurofilament levels in vivo.

Acta Neuropathol Commun · 2023 · PMC10334564 · PMID 37434215

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did not reach statistical significanceno p-value reported

31E9 and to a lesser extent 36C10 reduced the number of pHrodo-TDP-43-positive cells, while the moderate effect of 36C5 did not reach statistical significance.

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