Dyskerin and telomerase RNA component are sex-differentially associated with outcomes and Sunitinib response in patients with clear cell renal cell carcinoma.

For 85 ccRCC patients treated with Sunitinib in the IMmotion 150 cohort, the DKC1-high group exhibited significantly increased TERC expression (high vs low, P = 0.014); however, a highly significant increase was seen in female ( P = 0.0007) but not male ( P = 0.18) patients (Fig. 5 B).

also in 132,142 other papers

The difference between DKC1-high and low groups was close to but did not reach statistical significance ( P = 0.071).

also in 111,027 other papers