Although the study did not reach statistical significance for the improvement in overall survival with HD-MVAC, it showed an objective benefit in response rates and progression-free survival. 8 , 9 This led to HD-MVAC (dose-dense MVAC; dd-MVAC) becoming the preferred dosing schedule for this treatment combination.
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Systemic Treatment-Decision Algorithms in Muscle-Invasive Bladder Cancer: Clinical Complexities and Navigating for Improved Outcomes.
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