Barely Significant
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Rare coding variants in CHRNB2 reduce the likelihood of smoking.

Nat Genet · 2023 · PMC10335934 · PMID 37308787

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moderately significantP = 1.1 × 10 −5actually significant
Additionally, the Arg460Gly variant independently showed a moderately significant protective association with the heavy smoker phenotype (OR = 0.56; CI = 0.43–0.72; P = 1.1 × 10 −5 ).

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