A Phase I Randomized Trial of Once-Daily Versus Twice-Daily Recombinant Human Parathyroid Hormone (1-84) for Hypoparathyroidism.

JBMR Plus · 2023 · PMC10339078 · PMID 37457880

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a possible trendno p-value reported

In cohorts 1, 2, and 3 (but not cohort 4), a possible trend was observed for greater reductions in serum phosphorus at hours 12 to 24 of day 1 with BID dosing versus QD dosing (Fig. 5 A – C ).

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showed a trendno p-value reported

Indeed, cohorts that received supplemental calcium showed a trend for higher levels of serum calcium after rhPTH(1‐84) injection compared with cohorts that received no supplemental calcium.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.