Barely Significant
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Structural and Biochemical Investigation of Selected Pathogenic Mutants of the Human Dihydrolipoamide Dehydrogenase.

Int J Mol Sci · 2023 · PMC10341545 · PMID 37446004

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quite significantno p-value reported
A single-residue deletion in the midst of this structurally important helix may indeed lead to quite significant local—and even relayed or overall—structural rearrangements and/or improper folding.

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