The Influence of Nicotine on Trophoblast-Derived Exosomes in a Mouse Model of Pathogenic Preeclampsia.

Birth weights of pups were lower in the CD40L control group (1.31 ± 0.41 g, n = 9) than the nicotine-treated group (1.46 ± 0.35 g, n = 7), and placental weight was slightly lower in the control group (0.23 ± 0.03 g, n = 9) compared with nicotine-treated mice (0.26 ± 0.03 g, n = 5), though these results did not reach statistical significance ( Figure 2 B).

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