Lamin A/C Ablation Restricted to Vascular Smooth Muscle Cells, Cardiomyocytes, and Cardiac Fibroblasts Causes Cardiac and Vascular Dysfunction.

However, Lmna flox/flox SM22αCre mice showed a trend towards increased collagen content in the aortic arch and thoracic aorta ( Figure 4 B), which reached statistical significance in coronary arteries ( Figure 4 C).

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