Loss of epidermal glucocorticoid receptor protects against whole body metabolic dysfunction upon chronic corticosterone treatment.

Mol Metab · 2023 · PMC10345122 · PMID 37364709

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Basally, the expression of Crh was up-regulated in GR EKO vs control skin, and Pomc showed a trend towards up-regulation ( Figure 3 C), with significant higher Pomc levels in GR EKO keratinocytes ( Figure 3 D; 5-fold).

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