Identification of a psychiatric risk gene NISCH at 3p21.1 GWAS locus mediating dendritic spine morphogenesis and cognitive function.

BMC Med · 2023 · PMC10347724 · PMID 37443018

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hedged sentence

0.0410

closest p · 0.8× alpha

0.0410

boldest claim

The sentences

nominally significantP = 0.041actually significant

Differences in the total spine density between control neurons and those overexpressing NISCH were nominally significant (control, 5.57 ± 0.16 spines per 10 μm; overexpression of NISCH , 6.20 ± 0.26 spines per 10 μm, F (19, 19) = 2.72, df = 38, t = 2.11, P = 0.041, two-tailed Student’s t -tests; Fig. 2 A, B).

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