Whilst there is a favorable trend across the included studies, the degree of heterogeneity across their methodologies means the effects of topical gabapentin to improve pain in vulvodynia cannot be discerned.
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Effectiveness of topical gabapentin in the treatment of vulvodynia: a narrative synthesis.
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suggests a positive trend in pain improvement, there was neither a control arm nor a clear explanation in the methods to whether the study was standardized for all patients ( 36 ).
Data were presented graphically and showed a trend suggesting improvement in pain although statistical analysis was not conducted.