The precursors of ceramides (sphingomyelin, glucosylceramides) were also unaffected by long-term smoking although an increasing trend in the content of phospholipids (average increase of 58%) in smokers compared to non-smokers was observed.
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The effect of long-term cigarette smoking on selected skin barrier proteins and lipids.
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The sentences
We also observed a trend of increased gene expression of involucrin and TG1 which correlated with their elevated protein levels in the epidermis of smokers, although these results did not reach statistical significance.