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The muscle-enriched myokine Musclin impairs beige fat thermogenesis and systemic energy homeostasis via Tfr1/PKA signaling in male mice.

Nat Commun · 2023 · PMC10356794 · PMID 37468484

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Moreover, it has been reported that plasma ANP levels were trending lower, but did not reach statistical significance, in Musclin whole-body KO mice compared to WT controls following exercise training 40 .

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.