The prognostic and predictive role of tumor-infiltrating lymphocytes (FoxP3 + and CD8 +) and tumor-associated macrophages in early HER2 + breast cancer.

Breast Cancer Res Treat · 2023 · PMC10361875 · PMID 37428418

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0.0530

closest p · 1.1× alpha

0.0530

boldest claim

The sentences

did not reach statistical significancep = 0.053so close (0.05 < p ≤ 0.1)

For patients with a low CD8 + mTILs/FoxP3 + TILs ratio (n = 50), the differences in OS and BCSS did not reach statistical significance (80% vs. 44%, HR 0.36, 95% CI 0.13–1.02, p = 0.053 and 80% vs. 60%, HR 0.51, 95% CI 0.17–1.52, p = 0.227, respectively) (Fig. 4 c–d).

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