SIRT3 ameliorates diabetes-associated cognitive dysfunction via regulating mitochondria-associated ER membranes.

J Transl Med · 2023 · PMC10362714 · PMID 37481555

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failed to reach statistical significanceno p-value reported

Western blotting of synaptic proteins showed that diabetes reduced the expression of the presynaptic protein Synaptophysin (SYP) and the postsynaptic protein PSD 95, while overexpression of SIRT3 promoted the expression of SYP and PSD 95, although increased expression of PSD95 failed to reach statistical significance (see Additional file 2 : Fig.

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