In the dermis, WNT2 was the only Wnt signaling gene with log2FC > 1.5 (log2FC = 1.79), its FDR approached significance (FDR = 0.061), it was a leading edge gene (highest ranked) within the positively enriched Notch signaling Hallmark gene set within dermal GSEA data and was also present within the significantly enriched Multicellular organism development gene set (PANTHER GO-Slim Biological Process; P = 0.007).
← all excerpts
Unravelling morphoea aetiopathogenesis by next-generation sequencing of paired skin biopsies.
1
—
—