In addition to HERVH Xp22 .32 and HERVH 1p31.3 , another 6 HERVH proviruses were transcriptionally activated in EAC and this activation was more frequently associated with better survival, mirroring the effect of HERVH Xp22 .32, although this association did not reach statistical significance in both OCCAMS EAC cohorts (Figure 5A ).
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The transcriptional landscape of endogenous retroelements delineates esophageal adenocarcinoma subtypes.
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