In a study of 198 patients with a history of intracranial bleeding, Tzikas et al 13 found a higher prevalence of periprocedural major adverse events after LAAO device implantation; however, this effect did not reach statistical significance (5.4% vs 2.5%; P = .1).
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Intracranial bleeding and associated outcomes in atrial fibrillation patients undergoing percutaneous left atrial appendage occlusion: Insights from National Inpatient Sample 2016-2020.
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