Especially one category was highly significant in both: ‘response to hypoxia’ reached a p-value of 4.3 × 10 −5 in the fc fraction and of 9.4 × 10 −6 in the EV fraction ( Figure 3c , Supplementary Table S3).
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The sentences
The EV clusters are enriched in the lower left corner, indicating a significant trend towards a negative correlation with age in EVs.