Dopamine Transporter Knockout Rats Display Epigenetic Alterations in Response to Cocaine Exposure.

Biomolecules · 2023 · PMC10377455 · PMID 37509143

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showed a trendno p-value reported

Furthermore, as observed with KDM6B expression, female HET and KO rats showed a significant increase in BRD4 expression levels after chronic exposure to cocaine, an effect that only showed a trend in WT female rats.

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an increasing trendno p-value reported

Specifically, in response to cocaine, an increasing trend could be observed in the WT group, and there was a significant increase in KDM6B expression in HET and KO rats ( Figure 1 C).

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