Importantly, in this nonrandomized real-life cohort with selection criteria described above, the frequency of prior grade 2–4 aGVHD was similar to the earlier BMTCTN 0201 cohort in PB transplant at approximately 45%, with a slight trend toward less prior aGVHD in the BM group.
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Validated graft-specific biomarkers identify patients at risk for chronic graft-versus-host disease and death.
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Of note, aGVHD grade 2–4 before day 90 for PB and BM did not reach statistical significance.