Impact of the Recipient's Pre-Treatment Blood Lymphocyte Count on Intended and Unintended Effects of Anti-T-Lymphocyte Globulin in Allogeneic Hematopoietic Stem Cell Transplantation.

There was a weak trend towards a higher relapse rate among patients with low ALC on the day of the first ATLG administration compared to recipients in the upper two tertiles ( Figure 2 C; cumulative incidence at 3 years: 40% versus 32%; p = 0.12).

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Acute GVHD Grade III-IV, aGVHD-Associated Mortality, and Chronic GVHD The univariate analysis showed a trend towards higher incidence of aGVHD grade 3–4 in HSCT recipients with a top-tertile ALC (ALC high) on the first day of ATLG administration, compared to those of the low/intermediate-ALC group (cumulative incidence at 3 years: 28% versus 21%; p = 0.08).

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