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Diagnosis and augmentation therapy for alpha-1 antitrypsin deficiency: current knowledge and future potential.

Drugs Context · 2023 · PMC10379007 · PMID 37521109

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41 After 2 years of AAT treatment, a statistically significant reduction in the annual rate of CT lung density loss and the total lung capacity (TLC) was observed, whilst functional residual capacity alone or TLC plus functional residual capacity did not reach statistical significance.

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