Downregulation of PACAP and the PAC1 Receptor in the Basal Ganglia, Substantia Nigra and Centrally Projecting Edinger-Westphal Nucleus in the Rotenone model of Parkinson's Disease.

Int J Mol Sci · 2023 · PMC10380602 · PMID 37511603

Europe PMC DOI

hedged sentence

0.0530

closest p · 1.1× alpha

0.0530

boldest claim

The sentences

nearly significantp = 0.053so close (0.05 < p ≤ 0.1)

Our results do not support this, because a nearly significant ( p = 0.053) elevation of Adcyap1 mRNA expression occurred in the insular cortex that fits well with the observations of Broome et al.

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