Therapeutic Modulation of Cell Morphology and Phenotype of Diseased Human Cells towards a Healthier Cell State Using Lignin.

It showed a trend in increasing COL2A1, a healthy phenotypic marker of cartilage with 80 μg/mL OSL resulting in a 0.4-fold decrease in the expression of COLA12 and a 0.6-fold increase in the expression of COL2A1 ( Figure 2 A,B).

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