CXCL9 inhibition does not ameliorate disease in murine models of both primary and secondary hemophagocytic lymphohistiocytosis.

Analysis of intrahepatic leukocytes by flow cytometry showed a slight trend to increased leukocytes in prf1 −/− cxcl9 −/− mice that was not statistically significant (Fig. 4 d).

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Prf1 −/− cxcl9 −/− group did exhibit a trend toward larger spleen that did not reach statistical significance (Fig. 3 b).

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