Interestingly, we found that in mice with normal NPR‐C expression ( Npr3 WT mice), both PA103 and HFD increased lung expression of NPR‐C, although the effect of the latter did not reach statistical significance.
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Deletion of the <i>Npr3</i> gene increases severity of acute lung injury in obese mice.
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The sentences
There was a nonsignificant trend toward increased Npr3 expression in the lungs of WT mice fed HFD versus NC.