Exposure to unmethylated CpG oligonucleotides disrupts blood pressure circadian rhythms and placental clock gene network in pregnant rats.

Am J Physiol Heart Circ Physiol · 2023 · PMC10396276 · PMID 37352412

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0.0600

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The sentences

did not reach statistical significanceP = 0.06so close (0.05 < p ≤ 0.1)

Similar reductions in circulating maternal anti-inflammatory cytokines IL-4 and IL-10 were also observed in the ODN2395-treated rats compared with controls, but these differences did not reach statistical significance ( P = 0.06 and 0.08, respectively; Supplemental Table S5).

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