Mechanical forces suppress antiviral innate immune responses from asthmatic airway epithelial cells following rhinovirus infection.

Application of compression following RV-A1 infection suppressed both IFN-β and IFN-λ protein concentrations at 48, 72, and 96 hpi, though these reductions did not reach statistical significance ( Fig. 4, A and B ; individual virus-infected IFN protein data points at 48, 72, and 96 hpi are shown in Supplemental Fig.

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