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RGC-specific ATF4 and/or CHOP deletion rescues glaucomatous neurodegeneration and visual function.

Mol Ther Nucleic Acids · 2023 · PMC10400881 · PMID 37547290

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RGC-specific deletion of CHOP or both ATF4 and CHOP also protected RGC axons, although axon protection by ATF4 KO did not reach statistical significance ( Figures 1 C and 1D).

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