Notably, %CD69 + NK cells, a recognized marker of activation, were higher in patients with low MHC-I expression compared to high MHC-I expression, though this did not reach statistical significance (P=0.07) ( Supplemental Figure 5 ).
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Intratumoral NKp46<sup>+</sup> natural killer cells are spatially distanced from T and MHC-I<sup>+</sup> cells with prognostic implications in soft tissue sarcoma.
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