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A novel 3D spheroid model of rheumatoid arthritis synovial tissue incorporating fibroblasts, endothelial cells, and macrophages.

Front Immunol · 2023 · PMC10402919 · PMID 37545512

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Following SF stimulation, a 1.5-fold increase in the ratio outgrowth to core area was observed compared to basal medium although this did not reach statistical significance ( Figure 2B ).

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