Biomarkers for patients with Wilms tumor: a review.

Front Oncol · 2023 · PMC10405734 · PMID 37554168

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highly significantno p-value reported

A COG trial ( 74 ) reported the detection of ctDNA in the serum of 41/50 (82%) and urine of 13/50 (26%) patients with stage III/IV disease, and the agreement between serum ctDNA and tumor sequencing results was highly significant.

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did not reach statistical significanceno p-value reported

Although this skewing did not reach statistical significance, it agrees with the conclusion of most recent studies that MYCN mutations have prognostic value, whether anaplastic or not. 4.

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