Pan-American Guidelines for the treatment of SARS-CoV-2/COVID-19: a joint evidence-based guideline of the Brazilian Society of Infectious Diseases (SBI) and the Pan-American Association of Infectious Diseases (API).

Ann Clin Microbiol Antimicrob · 2023 · PMC10408214 · PMID 37550690

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did not reach statistical significanceno p-value reported

In patients with risk factors for severe disease, molnupiravir, as compared with placebo, reduced mortality (one RCT, n = 1433, absolute risk difference of − 1.0%; 95% CI − 2.0% to − 0.0%; high certainty in evidence) but did not reach statistical significance for hospitalisation (one RCT, n = 1433, absolute risk difference of − 2.0%; 95% CI − 4.0% to 1.0%; high certainty in evidence).

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