Carvedilol Versus Other Nonselective Beta Blockers for Variceal Bleeding Prophylaxis and Death: A Network Meta-analysis.

J Clin Transl Hepatol · 2023 · PMC10412710 · PMID 37577228

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did not reach statistical significanceno p-value reported

19 However, in that meta-analysis, the RR for failure in achieving a hemodynamic response with carvedilol [pooled RR: 0.67, 95% CI: (0.44–1.01)] did not reach statistical significance, and was likely caused by a type II error. 19 That meta-analysis included five trials with 175 subjects, whereas our study included 10 trials with 692 subjects.

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