Barely Significant
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Expression quantitative trait methylation analysis elucidates gene regulatory effects of DNA methylation: the Framingham Heart Study.

Sci Rep · 2023 · PMC10415314 · PMID 37563237

2
hedged sentences
0.0000
closest p · 0.0× alpha
0.0000
boldest claim

The sentences

nominally significantp < 1E−7actually significant
In the WHI, all but one of the 1000 cis CpG-transcript pairs from discovery in FHS replicated at a nominally significant p -value of 0.05 with matching effect directionality, while 997 replicated at p < 1E−7 with matching effect directionality.

also in 672 other papers

highly significantno p-value reported
Indeed, conditional analyses of nearby SNPs on select associations showed that the CpG-transcript associations are still highly significant.

also in 11,749 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.