There was no significant difference in SDHA expression in either the ipsilateral or contralateral hippocampus of 6-OHDA group rats compared to CN group rats ( Figures 3E , F ), while COX-I was numerically lower in both the ipsilateral and contralateral hippocampus of lesioned rats, but the difference compared to controls did not reach statistical significance.
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Pioglitazone enhances brain mitochondrial biogenesis and phase II detoxification capacity in neonatal rats with 6-OHDA-induced unilateral striatal lesions.
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