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Role of Neurotrophins in Orofacial Pain Modulation: A Review of the Latest Discoveries.

Int J Mol Sci · 2023 · PMC10419393 · PMID 37569811

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a clear trendno p-value reported
Discussion This literature screening considered the last ten years and shows a clear trend in the chosen topics to deepen the mechanisms underlying orofacial nociceptive transmission.

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an interesting trendno p-value reported
The results obtained by the screening of the selected articles show an interesting trend, in which the precise modulation of neurotrophin signaling could switch neurotrophins from being a “promoter” of pain to their beneficial neurotrophic role of supporting the nerves in their recovery, especially when a structural alteration is present, as in neuropathic pain.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.