Western blot analysis of tumor homogenates from the orthotopic VCaP xenografts also showed a trend of increase in both GR and l-CaD expression in the tumors treated with the antiandrogen (apalutamide), although the expressions were heterogeneous as expected based on our IHC analyses (Fig. 5G ).
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Glucocorticoid receptor-induced non-muscle caldesmon regulates metastasis in castration-resistant prostate cancer.
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