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Cathepsin B abundance, activity and microglial localisation in Alzheimer's disease-Down syndrome and early onset Alzheimer's disease; the role of elevated cystatin B.

Acta Neuropathol Commun · 2023 · PMC10426223 · PMID 37580797

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A similar pattern of decreased cathepsin D activity was also observed in samples of temporal cortex from individuals who have AD-DS, but this did not reach statistical significance.

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