Mesothelin-targeting T cell receptor fusion construct cell therapy in refractory solid tumors: phase 1/2 trial interim results.

Peak plasma cytokine levels of IFN-γ, IL-6 and TNF-α showed a trend toward dose dependency (Fig. 4a ), and the peak levels of these cytokines also correlated with increased risk of developing a higher-grade CRS (Fig. 4b ).

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