Circulating oxylipin and bile acid profiles of dexmedetomidine, propofol, sevoflurane, and S-ketamine: a randomised controlled trial using tandem mass spectrometry.

BJA Open · 2022 · PMC10430865 · PMID 37588789

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did not reach statistical significanceno p-value reported

EpOME and 5-HETE were unaffected, the decreases in 9- and 13-HODE (HODE, a precursor of 13-KODE) did not reach statistical significance, and a reduction in PGD2 was observed. 20 The effects on PGD2 could not be determined in the current study because of an excessive number of zero values, although 9-HODE and 13-KODE were significantly decreased.

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