Platelet-derived exerkine CXCL4/platelet factor 4 rejuvenates hippocampal neurogenesis and restores cognitive function in aged mice.

Although increased, the PF4 protein levels in platelets of young exercising mice (for 4 days) did not reach statistical significance when compared to standard-housed animals (2786 mean A.U. in standard-housed mice vs. 3969 mean A.U. in running mice; fold change: 1.42, p = 0.05, n = 5 mice per group).

also in 111,027 other papers