A comparison of the effects of NOAC and VKA therapy on the incidence of dementia in patients with atrial fibrillation: A systematic review and meta-analysis.

Clin Cardiol · 2023 · PMC10436784 · PMID 37366141

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did not reach statistical significanceno p-value reported

However, this protective effect did not reach statistical significance when comparing NOAC to VKA in the “based on treatment” group, which guaranteed the duration of action of the drug and was more likely to reflect the actual effect of the drugs in reducing dementia risk in AF patients.

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