However, we observed that female cases with MS displayed increased EAA relative to their non-MS counterparts (difference = 0.75, 95% CI 0.29–1.21, P female individuals = 1.92 x 10 −3 ), while male individuals with MS also indicated a trend toward increased EAA relative to male individuals without, but this did not reach statistical significance (difference = 1.29, 95% CI 0.072–2.51, P male individuals = 0.052) ( Figure 2B ).
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Evaluation of Cell-Specific Epigenetic Age Acceleration in People With Multiple Sclerosis.
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