Toll-like receptor 4 and Syk kinase shape dendritic cell-induced immune activation to major house dust mite allergens.

Front Med (Lausanne) · 2023 · PMC10442820 · PMID 37614946

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Blocking TLR4 on moDCs modified the induced cytokine profile by significantly reducing the induced IL-10 response and showed a trend toward reduced IL-12p70 levels, whereas IL-6 levels were unaffected ( Figure 5B ).

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